Ousted Yahoo CEO has cancer, WSJ reports | Internet & Media - CNET News:
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I was diagnosed with thyroid cancer in Nov., 1999. Surgery and radioactive iodine followed. In Dec., 2006, I found a lump in my neck that turned cancerous. Shortly thereafter, it was found to have metastasized throughout my body and to be untreatable and inoperable. I started a clinical trial with Sutent (sunitinib) since Apr., 2007. In Nov., 2013, the tumors began growing again and I was removed from the Sutent Clinical Trial. I started a clinical trial taking of CEDIRANIB on 04/09/14.
Monday, May 14, 2012
Physical Activity in Cancer Survivors Associated With Better Health Outcomes - Cancer Network
You know, I'm sure it's true that physical activity helps, but no one ever tells you what to do when you have Hand-Foot Syndrome so bad that you have trouble walking or when you're so anemic that you have no strength. Still, it's in interesting article.
Physical Activity in Cancer Survivors Associated With Better Health Outcomes - Cancer Network:
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Physical Activity in Cancer Survivors Associated With Better Health Outcomes - Cancer Network:
'via Blog this'
Thursday, May 10, 2012
Wednesday, April 18, 2012
Stress, Inflammation and Cancer | www.dailyrx.com
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Stress goes by many names, but on a cellular level that name is inflammation. A number of biological activities can cause inflammation, so can the stresses of unhealthy lifestyles.
It is easy to appreciate that some things, like a bacterial infection, cause inflammation. Fever, swelling and redness are all the classic signs.
But while the stress from a poor diet, obesity, or emotional turmoil is not as noticeable, the effects can be just as bad.
Consider taking steps to lower the levels of stress in your life.
In a recent journal article, a medical doctor from Johns Hopkins explained the molecular basis of stress and inflammation in thyroid cancer, and concludes that stress is a definite risk factor in the development of of the disease.
And the principles explained are just as applicable to any other form of cancer, or any other cell in the body.
Mingzhao Xing, M.D., from Johns Hopkins University School of Medicine states that oxidants are molecules that are unstable. That means that in order to regain their stability, they have to steal a piece of another molecule nearby. This creates a chain reaction, where each molecule steals from its neighbor, until they are all slightly different than they used to be.
Stress is normal, and the inflammation that stress creates can be the result of exercise, as well. But when the cellular repair mechanisms never get a break to catch up with the damage, all kinds of problems can surface.
The kind of constantly changing environment present in chronicinflammation is one of the major pre-dispositions to cancer formation. So, cancer can be thought of as a series of changes in a cell until all of the normal protective mechanisms are no longer present, and the cell starts to reproduce wildly.
The term in scientific literature that refers to the stress produced in inflammation is oxidative stress, in reference to the most powerful oxidant, oxygen.
In comparison to the series of molecular thefts started by an oxidant, anti-oxidants are generous molecules. They freely give pieces of themselves to all of the oxidants, without starting that chain reaction, and without turning into an oxidant themselves.
In the context of thyroid cancer, Dr. Xing supports her conclusion by referencing earlier research that shows high measured levels of oxidants correlates with levels of thyroid cancer in patients.
This makes sense, because medical literature has known for a long time that the thyroid is an especially sensitive organ to levels of radiation, and radiation itself is another cause of oxidation, the chain reaction of molecular stealing.
Dr. Xing says that autoimmune diseases, such as Grave's Disease of the thyroid, diabetes, and others, are associated with higher development of cancers, as well as a finding showing a naturally higher level of oxidation in patients.
Similarly, inflammatory diseases such as Crohn's and Ulcerative Colitis are well known to be closely associated with colon cancer development.
She concludes, as have many, that while the topic of inflammation is complicated, there seems to be a great deal of theoretical evidence that antioxidants such as Vitamin C and E should lower levels of cancer formation.
Unfortunately, inexplicably, decades of research have found this to not be the case, but support the role of omega 3 supplements like fish oil in reducing inflammation, and other dietary influences such as a diet heavy in animal fat and red meat in raising the index of inflammation in the human body.
Other studies suggest that long term use of non-steroidal anti inflammatory drugs such as aspirin and ibuprofen may lower rates of cancer formation, and studies looking at the use of aspirin in patients with heart disease tends to support this.
If given a chance, the body naturally has many mechanisms to repair lifestyle stress and the cellular damage it causes.
Dr. Xing states that her research is supported by the National Institutes of Health.
Thyroid Cancer
The American Cancer Society estimates that there are over 48,000 new cases of thyroid cancer each year in the United States, and 1,700 of these patients will succumb to the disease. Three out of every four diagnoses will be made in women, and in contrast to many other cancers, the diagnoses are often in younger people between the ages of 20 to 55.
The thyroid is an endocrine gland located in the front of the neck below the “Adam’s Apple”. It produces the thyroid hormonestriiodothyroinine (T3) and thyroxine (T4) in response to hormonal signals from the brain (anterior pituitary gland), which help control the body’s rate of metabolism. It also produces the hormone calcitonin, which helps regulate the amount of calcium in the body.
Thursday, April 5, 2012
Nebraska Legislature passes bills dealing with chemotherapy, alcopops, school testing
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Nebraska lawmakers gave 42-0 final approval Monday to a bill (LB882) under which oral chemotherapy will be treated the same as intravenous cancer treatments for insurance purposes.
The bill's sponsor, Sen. Jeremy Nordquist of Omaha, said the lack of parity in coverage between intravenous and oral chemotherapy medications was a growing problem, with some cancer treatments costing $5,000 to $10,000 a month.
He said his bill would ensure that patients and doctors could make decisions about the course of treatment based on what would provide the best care, not what insurance companies deemed the most cost-effective.
Research shows that when confronted with the reality of high out-of-pocket expenses, cancer patients forgo expensive therapies and often discontinue treatments, in part because they do not want to saddle their families with unmanageable debt, Nordquist said.
Because oncologists know how expensive oral medications can be, he said, they often do not prescribe them -- even when they think that would be the better option.
The actuarial and benefits consulting firm Milliman Inc. did a study in 2010 that estimated requiring similar coverage for oral chemotherapy would cost less than $6 a year per person in most insurance plans. The study was paid for by GlaxoSmithKline, which makes and is developing oral chemotherapy drugs.
In other action Monday, lawmakers:
* Gave 37-6 final approval to a bill that would gut a recent Nebraska Supreme Court ruling that said so-called alcopops must be taxed as hard liquor instead of like beer. The high court had ruled that flavored malt drinks -- such as Mike's Hard Lemonade and Smirnoff Ice -- should be taxed the same as hard liquor. Beer is taxed at 31 cents a gallon, spirits at $3.75 a gallon.
The bill (LB824) was introduced by Sen. Russ Karpisek of Wilber in anticipation of the high court's ruling. Lancaster County District Judge John Colborn ruled earlier that under state law, the drinks should be considered spirits, not beer, because they contain distilled alcohol. The state appealed that ruling to the high court.
Colborn's ruling was in response to a lawsuit filed by a mother and three groups that combat underage drinking. They say alcopops are marketed toward young people, and an increase in price -- a likely result of a tax change -- would act as a deterrent.
* Voted 46-0 to give final approval to a bill (LB870) to add other measures of accountability to test scores in judging schools.
The bill will establish an accountability system to measure the performance of individual public schools and school districts beginning with the 2012-13 school year. It will combine multiple measures, including graduation rates, student growth and student improvement on statewide assessments.
It was sponsored by Sen Greg Adams of York, chairman of the Education Committee. Adams said it broadened the picture of schools, because there was more to a school, or a school district, than test scores. Some Nebraska schools -- mostly because of demographics -- may never show the kind of proficiency on reading, math and writing tests that is expected of them. But they should get credit for improvement.
* Gave 44-0 final approval to a bill (LB933) meant to build on a truancy law passed in 2010. Families have complained to senators and anyone who would listen that they have been hurt by the law, which requires that more than 20 absences in a school year -- excused or unexcused -- be reported to the county attorney, who then investigates and decides whether to take action.
The bill passed Monday would allow schools to decide whether to report excused absences. If there is even one unexcused absence among the 20, the report would be required.
* Voted 46-0 to pass a bill (LB799) establishing that negligent child abuse resulting in the death of a child and negligent child abuse that results in serious bodily injury are felonies. Previously, regardless of the injuries caused to the child, negligent child abuse was a misdemeanor. The bill was by Sen. Abbie Cornett of Bellevue.
Reach Kevin O'Hanlon at 402-473-2682 or kohanlon@journalstar.com.
Posted in Statehouse, Unicameral, Nebraska on Monday, April 2, 2012 1:15 pm Updated: 6:20 pm. | Tags: Chemotherapy, Jeremy Nordquist, Legislature, Insurance, Russ Karpisek, Greg Adams
Read more: http://journalstar.com/news/state-and-regional/statehouse/legislature-passes-bills-dealing-with-chemotherapy-alcopops-school-testing/article_dc9339d7-338d-5731-8087-d1b453320f5c.html#ixzz1rBL7oyLs
Foods to Avoid If You Have Dry Mouth
By Lisa Fayed, About.com Guide
Updated April 02, 2012
About.com Health's Disease and Condition content is reviewed by our Medical Review Board
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Dry mouth is a common side effect of radiation therapy that affects cancer patients who have undergone treatment to the head and neck region. It is caused by damage to the salivary glands when they are exposed to radiation. When someone has dry mouth, eating can be a challenge, resulting in difficulty with chewing and swallowing, as there is little or no saliva to help break down the food. Mouth sores and infections can also develop, contributing to eating problems. Even speaking can be difficult for dry mouth sufferers.
Some foods are easier to eat than others. For many, learning which foods can be tolerated is through trial and error. However, there are some foods that people with dry mouth should avoid for several different reasons.
Foods to Avoid
Crusty Breads: Crusty breads can be difficult to chew and swallow. They can also irritate the inside of the mouth. If you like to eat bread, choose a softer variety. You may also try dipping bread in sauces or gravies. Basic Recipe for White BreadAcidic Foods: Foods with acidic ingredients like lemon and vinegar can definitely irritate the inside of the mouth, especially if you have mouth sores.
Salty Foods: Like acidic foods, salty foods can irritate the inside of the mouth.
Spicy Foods: Without saliva to protect the mucosa (the lining of inside of the mouth, spicy foods can be especially irritating.
Sugary Foods and Drinks: Saliva serves many purposes in digestion and one of them is to breakdown the sugars in food. One of the reasons why people suffering from dry mouth are at an increased risk of developing dental problems like decay and infections is because sugars aren't properly being properly broken down. Due to the increased risk, it's best to avoid foods and drinks that contain sugar. How to Choose a Dentist
Dry Foods: Dry foods likes crackers, toasted breads, and chips can be extremely difficult to swallow if you have dry mouth. These types of foods depend on saliva to become soft for easier chewing and swallowing. Dry foods with sharp edges like crackers and tortilla chips and can also irritate the inside of your mouth. You can dip crackers and toasted breads in dips and sauces to make swallowing easier, but it may not not work for everyone. Some find success in dipping crackers in water or milk before eating.
Tough Meats Meats can be especially challenging to eat for dry mouth sufferers. It is best to avoid tough meats altogether, but softer meats can be tolerated by many with a little modification. Try adding sauces and gravies to meats to help effectively chew and swallow. Remember to frequently take sips during meals -- it can help with swallowing and to also keep the mouth wet during meals. Gravy and Sauce Recipes
Combating Dry Mouth Takes Effort, But Can Be Controlled
Chronic dry mouth can be frustrating, especially for long term sufferers. Eating can become such a challenge and chore that some people begin to eat less, compromising their nutritional health. It doesn't have to be this way, though. Dry mouth can be managed a number of ways, with both pharmaceutical and OTC remedies. Some patients find additional relief by adding a humidifier to their bedroom and learning how to breathe through their noses instead of mouths. There are many different ways to help combat dry mouth caused by radiation therapy. Learn what you can do to combat dry mouth.
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