Exploring the Anticancer Potential of Valproic Acid in Advanced Thyroid Cancer
Phase II Trial of Valproic Acid in Patients with Advanced Thyroid Cancers of Follicular Cell Origin (NCI-10-C-0041). See the protocol summary.
Dr. Electron Kebebew, NCI Center for Cancer Research
Most thyroid cancers, especially when found early, are highly treatable and usually curable. About 90 percent of thyroid cancers are either of the papillary or the folliculartype, both of which arise in the follicular cells of the thyroid. The cells of these tumors are usually well differentiated, meaning that they appear more similar to regular thyroid cells than cells of the rarer and more aggressive medullary and anaplastic types. Differentiated thyroid cancers are usually amenable to surgical resection and systemic therapy withradioactive iodine, which is readily taken up by the thyroid.